Güncel bilimsel çalışmalara ve yayınlara genel bakış

Long COVID ile ilgili bilimsel araştırmalar dünya çapında yürütülmektedir. Buna göre bu konudaki yayın sayısı oldukça fazladır. Çalışmalar ve sonuçları ilgi, önem ve kalite açısından farklılık göstermektedir. Bu nedenle ilgili yayınları bulmak zor olabilir. Bu nedenle Robert Koch Enstitüsü (RKI) ve uluslararası üne sahip araştırmacılar bu bölümde bize literatür önerilerini sunmaktadır.

Liste, öncelikle uluslararası uzmanlık dergilerinde yayınlanmış İngilizce bilimsel yayınları içermektedir. Ancak birkaç seçilmiş Almanca uzmanlık makalesi de bulunmaktadır. Liste eksiksiz olma iddiasında değildir. RKI ve uluslararası uzmanlarımız yayınları kendi standartlarına göre seçmiştir. Daha iyi bir genel bakış için, bazıları başka konu alanlarıyla da ilgili olsa da, yayınlar kategoriler halinde sınıflandırılmıştır.

Buna ek olarak, RKI her ay epidemiyoloji ve halk sağlığı ile ilgili güncel yayınlardan bir seçki sunmaktadır.

Yeni çalışmalar 2023


Long-term outcomes of SARS-CoV-2 variants and other respiratory infections: evidence from the Virus Watch prospective cohort in England. 
Beale S, Yavlinsky A, Fong WLE, et. al. Epidemiol Infect. 2024 May 10;152:e77. doi: 10.1017/S0950268824000748. 

Long COVID: lights and shadows on the clinical characterization of this emerging pathology. 
Cogliandro V, Bonfanti P. New Microbiol. 2024 May;47(1):15-27. 

Lower prevalence of post-Covid-19 Condition following Omicron SARS-CoV-2 infection. 
de Bruijn S, van Hoek AJ, Mutubuki EN, et al. Heliyon. 2024 Mar 30;10(7):e28941. doi: 10.1016/j.heliyon.2024.e28941. eCollection 2024 Apr 15. 

The Aftermath of COVID-19: Exploring the Long-Term Effects on Organ Systems. 
Golzardi M, Hromić-Jahjefendić A, Šutković J, et al. Biomedicines. 2024 Apr 20;12(4):913. doi: 10.3390/biomedicines12040913. 

Comparison of post-COVID-19 symptoms in patients infected with the SARS-CoV-2 variants delta and omicron-results of the Cross-Sectoral Platform of the German National Pandemic Cohort Network (NAPKON-SUEP). 
Hopff SM, Appel KS, Miljukov O, et al. Infection. 2024 May 3. doi: 10.1007/s15010-024-02270-5. Online ahead of print. 

Biases and limitations in observational studies of Long COVID prevalence and risk factors: A rapid systematic umbrella review. 
Hua MJ, Butera G, Akinyemi O, Porterfield D. PLoS One. 2024 May 2;19(5):e0302408. doi: 10.1371/journal.pone.0302408. eCollection 2024. 

Prevalence and risk factors for long COVID among adults in Scotland using electronic health records: a national, retrospective, observational cohort study. 
Jeffrey K, Woolford L, Maini R, et al. EClinicalMedicine. 2024 Apr 11;71:102590. doi: 10.1016/j.eclinm.2024.102590. eCollection 2024 May. 

The Spectrum of Postacute Sequelae of COVID-19 in Children: From MIS-C to Long COVID. 
Kane AS, Godfrey M, Noval Rivas M, et al. Annu Rev Virol. 2024 Apr 17. doi: 10.1146/annurev-virology-093022-011839. Online ahead of print. 

Cross-sectional surveillance study of long COVID in Toyonaka city, Osaka prefecture, Japan. 
Kutsuna S, Onozuka D, Asano K, Matsunami K, Matsuoka T.J Infect Chemother. 2024 Jun;30(6):511-515. doi: 10.1016/j.jiac.2023.12.006. Epub 2023 Dec 14. 

Long COVID: Long-Term Impact of SARS-CoV2. 
Makhluf H, Madany H, Kim K. Diagnostics (Basel). 2024 Mar 28;14(7):711. doi: 10.3390/diagnostics14070711. 

Post-COVID conditions following COVID-19 vaccination: a retrospective matched cohort study of patients with SARS-CoV-2 infection. 
Malden DE, Liu IA, Qian L, et al. Nat Commun. 2024 May 22;15(1):4101. doi: 10.1038/s41467-024-48022-9. 

Post-Covid-19 condition (Long Covid) in children and young people 12 months after infection or reinfection with the Omicron variant: a prospective observational study. 
Pinto Pereira SM, Nugawela MD, Stephenson T, et al. Sci Rep. 2024 Apr 30;14(1):9957. doi: 10.1038/s41598-024-60372-4. 

Defining the Subtypes of Long COVID and Risk Factors for Prolonged Disease: Population-Based Case-Crossover Study. 
Resendez S, Brown SH, Ruiz Ayala HS, et al. JMIR Public Health Surveill. 2024 Apr 30;10:e49841. doi: 10.2196/49841. 

Towards understanding post-COVID-19 condition: A systematic meta-analysis of transcriptomic alterations with sex-specific insights. 
Rusu EC, Monfort-Lanzas P, Bertran L, et al .Comput Biol Med. 2024 Jun;175:108507. doi: 10.1016/j.compbiomed.2024.108507. Epub 2024 Apr 22. 

Machine learning to understand risks for severe COVID-19 outcomes: a retrospective cohort study of immune-mediated inflammatory diseases, immunomodulatory medications, and comorbidities in a large US health-care system. 
Wei Q, Mease PJ, Chiorean M, et al. Lancet Digit Health. 2024 May;6(5):e309-e322. doi: 10.1016/S2589-7500(24)00021-9.  


Using a data-driven approach to define post-COVID conditions in US electronic health record data.  
Andersen KM, Khan FL, Park PW, et al. PLoS One. 2024 Apr 5;19(4):e0300570. doi: 10.1371/journal.pone.0300570. eCollection 2024.  

A Comprehensive Review of Neurodegenerative Manifestations of SARS-CoV-2.  
Bedran D, Bedran G, Kote S.Vaccines (Basel). 2024 Feb 21;12(3):222. doi: 10.3390/vaccines12030222.  

UK biobank: Enhanced assessment of the epidemiology and long-term impact of coronavirus disease-2019.  
Feng Q, Lacey B, Bešević J, et al. Camb Prism Precis Med. 2023 Aug 29;1:e30. doi: 10.1017/pcm.2023.18. eCollection 2023.  

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches.  
Gheorghita R, Soldanescu I, Lobiuc A, et al. 2024 Mar 4;15:1344086. doi: 10.3389/fimmu.2024.1344086. eCollection 2024.  

Prevalence and Trajectories of Post-COVID-19 Neurological Manifestations: A Systematic Review and Meta-Analysis.  
Giussani G, Westenberg E, Garcia-Azorin D, et al.; Global COVID-19 Neuro Research Coalition.Neuroepidemiology. 2024;58(2):120-133. doi: 10.1159/000536352. Epub 2024 Jan 25.  

Symptom trajectories of post-COVID sequelae in patients with acute Delta or Omicron infection in Bergen, Norway.  
Iversen A, Blomberg B, Haug K, et al. Front Public Health. 2024 Mar 5;12:1320059. doi: 10.3389/fpubh.2024.1320059. eCollection 2024.  

Long COVID's Impact on Patients, Workers, & Society: A review.  
Kavanagh KT, Cormier LE, Pontus C, et al. Medicine (Baltimore). 2024 Mar 22;103(12):e37502. doi: 10.1097/MD.0000000000037502.  

Subphenotypes of self-reported symptoms and outcomes in long COVID: a prospective cohort study with latent class analysis.  
Kitsios GD, Blacka S, Jacobs JJ, et al. BMJ Open. 2024 Mar 14;14(3):e077869. doi: 10.1136/bmjopen-2023-077869.  

Cross-sectional population-based estimates of a rural-urban disparity in prevalence of long COVID among Michigan adults with polymerase chain reaction-confirmed COVID-19, 2020-2022.  
MacCallum-Bridges CL, Hirschtick JL, Allgood KL, et al. 2024 Mar;40(2):303-313. doi: 10.1111/jrh.12807. Epub 2023 Nov 16.  

The impact of COVID-19 vaccination prior to SARS-CoV-2 infection on prevalence of long COVID among a population-based probability sample of Michiganders, 2020-2022.  
MacCallum-Bridges C, Hirschtick JL, Patel A, et al. Epidemiol. 2024 Apr;92:17-24. doi: 10.1016/j.annepidem.2024.02.007. Epub 2024 Feb 19.  

Gender differences in symptomatology, socio-demographic information and quality of life in Spanish population with long COVID condition: a cross-sectional study.  
Marcilla-Toribio I, Moratalla-Cebrián ML, Notario-Pacheco B, et al. Front Public Health. 2024 Mar 21;12:1355973. doi: 10.3389/fpubh.2024.1355973. eCollection 2024.  

Vaccine Effectiveness Against Long COVID in Children.  
Razzaghi H, Forrest CB, Hirabayashi K, Wu Q, Allen AJ, et al. RECOVER CONSORTIUM. Pediatrics. 2024 Apr 1;153(4):e2023064446. doi: 10.1542/peds.2023-064446.  

Risk factors and early preventive measures for long COVID in non-hospitalized patients: analysis of a large cohort in the United Arab Emirates.  
Saheb Sharif-Askari F, Ali Hussain Alsayed H, Saheb Sharif-Askari N, et al. Public Health. 2024 May;230:198-206. doi: 10.1016/j.puhe.2024.02.031. Epub 2024 Apr 3.  

Updated Clinical Practice Guidelines for the Diagnosis and Management of Long COVID.  
Seo JW, Kim SE, Kim Y, et al. Infect Chemother. 2024 Mar; 56(1):122-157. doi: 10.3947/ic.2024.0024. Epub 2024 Mar 13.  

From Acute Infection to Prolonged Health Consequences: Understanding Health Disparities and Economic Implications in Long COVID Worldwide.  
Sweis JJG, Alnaimat F, Esparza V, et al.Int J Environ Res Public Health. 2024 Mar 11;21(3):325. doi: 10.3390/ijerph21030325.  

Long COVID in a highly vaccinated but largely unexposed Australian population following the 2022 SARS-CoV-2 Omicron wave: a cross-sectional survey.  
Woldegiorgis M, Cadby G, Ngeh S, et al. Med J Aust. 2024 Apr 1;220(6):323-330. doi: 10.5694/mja2.52256. Epub 2024 Mar 20. 


Unravelling shared mechanisms: insights from recent ME/CFS research to illuminate long COVID pathologies. 
Annesley SJ, Missailidis D, Heng B, et al. Trends Mol Med. 2024 Mar 4:S1471-4914(24)00028-5. doi: 10.1016/j.molmed.2024.02.003. Online ahead of print. 

What is the impact of long-term COVID-19 on workers in healthcare settings? A rapid systematic review of current evidence. 
Cruickshank M, Brazzelli M, Manson P, et al .PLoS One. 2024 Mar 5;19(3):e0299743. doi: 10.1371/journal.pone.0299743. eCollection 2024. 

Developing effective strategies to optimize physical activity and cardiorespiratory fitness in the long Covid population- The need for caution and objective assessment. 
Faghy MA, Duncan R, Hume E, et al. Prog Cardiovasc Dis. 2024 Mar 8:S0033-0620(24)00039-2. doi: 10.1016/j.pcad.2024.03.003. Online ahead of print. 

Outcome predictors of post-COVID conditions in the European Academy of Neurology COVID-19 registry. 
Leone MA, Helbok R, Bianchi E, et al. J Neurol. 2024 Mar 4. doi: 10.1007/s00415-024-12212-8. Online ahead of print. 

IA-PACS-CFS: a double-blinded, randomized, sham-controlled, exploratory trial of immunoadsorption in patients with chronic fatigue syndrome (CFS) including patients with post-acute COVID-19 CFS (PACS-CFS). 
Preßler H, Machule ML, Ufer F, et al. Trials. 2024 Mar 7;25(1):172. doi: 10.1186/s13063-024-07982-5. 

Postacute Sequelae of SARS-CoV-2 in Children. 
Rao S, Gross RS, Mohandas S, et al. Pediatrics. 2024 Mar 1;153(3):e2023062570. doi: 10.1542/peds.2023-062570. 

Unmasking the long-term effects: unravelling neuropsychiatric and neurological consequences of COVID-19. 
Tariq M, Mahak F, Kumar R, et al. Ann Med Surg (Lond). 2024 Jan 4;86(3):1490-1495. doi: 10.1097/MS9.0000000000001624. eCollection 2024 Mar. 

Prevalence of mental health conditions and brain fog in people with long COVID: A systematic review and meta-analysis. 
van der Feltz-Cornelis C, Turk F, Sweetman J, et al. Gen Hosp Psychiatry. 2024 Feb 27;88:10-22. doi: 10.1016/j.genhosppsych.2024.02.009. Online ahead of print. 

Yorumlar

Long COVID: major findings, mechanisms and recommendations.
Davis HE, McCorkell L, Vogel JM, et al. Nat Rev Microbiol. 2023 Mar;21(3):133-146. doi: 10.1038/s41579-022-00846-2. Epub 2023 Jan 13.
 
Unexplained post-acute infection syndromes.
Choutka J, Jansari V, Hornig M, et al. Nat Med. 2022 May;28(5):911-923. doi: 10.1038/s41591-022-01810-6. Epub 2022 May 18.
 
Post-COVID Syndrome.
Hallek M, Adorjan K, Behrends U, et al. Dtsch Arztebl Int. 2023 Jan 27;120(4):48-55. doi: 10.3238/arztebl.m2022.0409.
 
Post COVID und Post-Vakzin-Syndrom: Die Pandemie nach der Pandemie.
Scheibenbogen C, Renz-Polster H, Hohberger B, et al. Dtsch Arztebl 2023; 120(13):566-570.

Hastalık/vaka tanımları

A clinical case definition for post COVID-19 condition in children and adolescents by expert consensus.
World Health Organisation. 2023 Feb 16. 
 
Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection.
Thaweethai T, Jolley SE, Karlson EW, et al. JAMA. 2023 Jun 13;329(22):1934-1946. doi: 10.1001/jama.2023.8823.
 
A core outcome set for post-COVID-19 condition in adults for use in clinical practice and research: an international Delphi consensus study.
Munblit D, Nicholson T, Akrami A, et al. Lancet Respir Med. 2022 Jul;10(7):715-724. doi: 10.1016/S2213-2600(22)00169-2. Epub 2022 Jun 14.
 
Post-COVID-19 condition in children: a COS is urgently needed.
Munblit D, Buonsenso D, Sigfrid L, et al. Lancet Respir Med. 2022 Jul;10(7):628-629. doi: 10.1016/S2213-2600(22)00211-9. Epub 2022 Jun 14.

Temel araştırma, hastalık geliştirme

Brainstem volume changes in myalgic encephalomyelitis/chronic fatigue syndrome and long COVID patients.
Thapaliya K, Marshall-Gradisnik S, Barth M, et al. Front Neurosci. 2023 Mar 2;17:1125208. doi: 10.3389/fnins.2023.1125208. 
 
Deficient GABABergic and glutamatergic excitability in the motor cortex of patients with long-COVID and cognitive impairment.
Manganotti P, Michelutti M, Furlanis G, et al. Clin Neurophysiol. 2023 Jul;151:83-91. doi: 10.1016/j.clinph.2023.04.010. 
 
Cerebral hypoperfusion in post-COVID-19 cognitively impaired subjects revealed by arterial spin labeling MRI.
Ajčević M, Iscra K, Furlanis G, et al. Sci Rep. 2023 Apr 10;13(1):5808. doi: 10.1038/s41598-023-32275-3.
 
SARS-CoV-2 is associated with changes in brain structure in UK Biobank.
Douaud G, Lee S, Alfaro-Almagro F, et al. Nature. 2022 Apr;604(7907):697-707. doi: 10.1038/s41586-022-04569-5. 
 
Cerebrospinal Fluid Analysis Post-COVID-19 Is Not Suggestive of Persistent Central Nervous System Infection.
Schweitzer F, Goereci Y, Franke C, et al. Ann Neurol. 2022 Jan;91(1):150-157. doi: 10.1002/ana.26262. 
 
Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS).
Haffke M, Freitag H, Rudolf G, et al. .J Transl Med. 2022 Mar 22;20(1):138. doi: 10.1186/s12967-022-03346-2.
 
Serum of Post-COVID-19 Syndrome Patients with or without ME/CFS Differentially Affects Endothelial Cell Function In Vitro.
Flaskamp L, Roubal C, Uddin S, et al. Cells. 2022 Aug 2;11(15):2376. doi: 10.3390/cells11152376.
 
Orthostatic Challenge Causes Distinctive Symptomatic, Hemodynamic and Cognitive Responses in Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Vernon SD, Funk S, Bateman L, et al. Front Med (Lausanne). 2022 Jun 23;9:917019. doi: 10.3389/fmed.2022.917019. 
 
Coronary microvascular health in symptomatic patients with prior COVID-19 infection: an updated analysis.
Ahmed AI, Al Rifai M, Alahdab F, et al. Eur Heart J Cardiovasc Imaging. 2023 May 31:jead118. doi: 10.1093/ehjci/jead118. 
 
Long-Term Adverse Effects of Mild COVID-19 Disease on Arterial Stiffness, and Systemic and Central Hemodynamics: A Pre-Post Study.
Podrug M, Koren P, Dražić Maras E, et al. .J Clin Med. 2023 Mar 8;12(6):2123. doi: 10.3390/jcm12062123.
 
The potential role of ischaemia-reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and therapeutic implications.
Kell DB, Pretorius E.Biochem J. 2022 Aug 31;479(16):1653-1708. doi: 10.1042/BCJ20220154
 
Proteomic profiling demonstrates inflammatory and endotheliopathy signatures associated with impaired cardiopulmonary exercise hemodynamic profile in Post Acute Sequelae of SARS-CoV-2 infection (PASC) syndrome.
Singh I, Leitner BP, Wang Y, et al. Pulm Circ. 2023 Apr 1;13(2):e12220. doi: 10.1002/pul2.12220. 
 
Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8+β7 integrin+ T cells and anti-SARS-CoV-2 IgA response.
Santa Cruz A, Mendes-Frias A, Azarias-da-Silva M, et al. Nat Commun. 2023 Mar 30;14(1):1772. doi: 10.1038/s41467-023-37368-1.
 
Pulmonary Dysfunction after Pediatric COVID-19.
Heiss R, Tan L, Schmidt S, et al. Radiology. 2023 Mar;306(3):e221250. doi: 10.1148/radiol.221250. 
 
Physical phenotype of blood cells is altered in COVID-19.
Kubánková M, Hohberger B, Hoffmanns J, et al. Biophys J. 2021 Jul 20;120(14):2838-2847. doi: 10.1016/j.bpj.2021.05.025. 
 
Post-COVID-19 Syndrome: Retinal Microcirculation as a Potential Marker for Chronic Fatigue.
Schlick S, Lucio M, Wallukat G, et al. Int J Mol Sci. 2022 Nov 8;23(22):13683. doi: 10.3390/ijms232213683.
 
The immunology and immunopathology of COVID-19.
Merad M, Blish CA, Sallusto F, et al. Science. 2022 Mar 11;375(6585):1122-1127. doi: 10.1126/science.abm8108.

Semptomlar

Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection.
Thaweethai T, Jolley SE, Karlson EW, et al.  JAMA. 2023 Jun 13;329(22):1934-1946. doi: 10.1001/jama.2023.8823.
 
A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity.
Kedor C, Freitag H, Meyer-Arndt L, et al. Nat Commun. 2022 Aug 30;13(1):5104. doi: 10.1038/s41467-022-32507-6.
 
Trajectories of the evolution of post-COVID-19 condition, up to two years after symptoms onset.
Servier C, Porcher R, Pane I, et al. Int J Infect Dis. 2023 Aug;133:67-74. doi: 10.1016/j.ijid.2023.05.007. 
 
Long-term neurologic outcomes of COVID-19.
Xu E, Xie Y, Al-Aly Z.Nat Med. 2022 Nov;28(11):2406-2415. doi: 10.1038/s41591-022-02001-z. 
 
Impact of fatigue as the primary determinant of functional limitations among patients with post-COVID-19 syndrome: a cross-sectional observational study.
Walker S, Goodfellow H, Pookarnjanamorakot P, et al. BMJ Open. 2023 Jun 7;13(6):e069217. doi: 10.1136/bmjopen-2022-069217.
 
Chronic Fatigue and Postexertional Malaise in People Living With Long COVID: An Observational Study.
Twomey R, DeMars J, Franklin K, et al. Phys Ther. 2022 Apr 1;102(4):pzac005. doi: 10.1093/ptj/pzac005.
 
Cognitive impairment in young adults with post COVID-19 syndrome.
Herrera E, Pérez-Sánchez MDC, San Miguel-Abella R, et al. Sci Rep. 2023 Apr 19;13(1):6378. doi: 10.1038/s41598-023-32939-0.
 
Long-term cardiovascular outcomes of COVID-19.
Xie Y, Xu E, Bowe B, et al. Nat Med. 2022 Mar;28(3):583-590. doi: 10.1038/s41591-022-01689-3. 
 
Long-term cardiovascular outcomes in COVID-19 survivors among non-vaccinated population: A retrospective cohort study from the TriNetX US collaborative networks.
Wang W, Wang CY, Wang SI, et al. EClinicalMedicine. 2022 Nov;53:101619. doi: 10.1016/j.eclinm.2022.101619. 
 
Impaired health-related quality of life in long-COVID syndrome after mild to moderate COVID-19.
Malesevic S, Sievi NA, Baumgartner P, et al. Sci Rep. 2023 May 12;13(1):7717. doi: 10.1038/s41598-023-34678-8.
 
Two-year follow-up of patients with post-COVID-19 condition in Sweden: a prospective cohort study.
Wahlgren C, Forsberg G, Divanoglou A, et al. Lancet Reg Health Eur. 2023 May;28:100595. doi: 10.1016/j.lanepe.2023.100595. 

Diyagnostik

Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of autonomic dysfunction in patients with post-acute sequelae of SARS-CoV-2 infection (PASC).
Blitshteyn S, Whiteson JH, Abramoff B, et al. PM R. 2022 Oct;14(10):1270-1291. doi: 10.1002/pmrj.12894. 

Terapi

The relevance of pacing strategies in managing symptoms of post-COVID-19 syndrome.
Ghali A, Lacombe V, Ravaiau C, et al. J Transl Med. 2023 Jun 8;21(1):375. doi: 10.1186/s12967-023-04229-w.
 
Rehabilitative interventions in patients with persistent post COVID-19 symptoms-a review of recent advances and future perspectives.
Gloeckl R, Leitl D, Schneeberger T, et al. Eur Arch Psychiatry Clin Neurosci. 2023 Jun 16. doi: 10.1007/s00406-023-01631-9. 
 
Fighting Post-COVID and ME/CFS - development of curative therapies.
Scheibenbogen C, Bellmann-Strobl JT, Heindrich C, et al. Front Med (Lausanne). 2023 Jun 15;10:1194754. doi: 10.3389/fmed.2023.1194754. 
 
Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial.
Bramante CT, Buse JB, Liebovitz DM, et al. Lancet Infect Dis. 2023 Jun 8:S1473-3099(23)00299-2. doi: 10.1016/S1473-3099(23)00299-2. 

ME/CFS

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome is common in post-acute sequelae of SARS-CoV-2 infection (PASC): Results from a post-COVID-19 multidisciplinary clinic.
Bonilla H, Quach TC, Tiwari A, et al. Front Neurol. 2023 Feb 24;14:1090747. doi: 10.3389/fneur.2023.1090747. 
 
Orthostatic Symptoms and Reductions in Cerebral Blood Flow in Long-Haul COVID-19 Patients: Similarities with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Campen CLMCV, Rowe PC, Visser FC. Medicina (Kaunas). 2021 Dec 24;58(1):28. doi: 10.3390/medicina58010028.
 
Orthostatic Intolerance in Long-Haul COVID after SARS-CoV-2: A Case-Control Comparison with Post-EBV and Insidious-Onset Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients.
van Campen CLMC, Visser FC. Healthcare (Basel). 2022 Oct 17;10(10):2058. doi: 10.3390/healthcare10102058.
 
ME/CFS and Long COVID share similar symptoms and biological abnormalities: road map to the literature.
Komaroff AL, Lipkin WI. Front Med (Lausanne). 2023 Jun 2;10:1187163. doi: 10.3389/fmed.2023.1187163.

Halk Sağlığı

Long COVID: long-term health outcomes and implications for policy and research.
Al-Aly Z, Agarwal A, Alwan N, et al. Nat Rev Nephrol. 2023 Jan;19(1):1-2. doi: 10.1038/s41581-022-00652-2.
 
Long COVID Through a Public Health Lens: An Umbrella Review.
Nittas V, Gao M, West EA, et al. Public Health Rev. 2022 Mar 15;43:1604501. doi: 10.3389/phrs.2022.1604501. 
 
Long COVID – eine Herausforderung für Public Health und Gesundheitsforschung. 
Nübel J, Sarganas G, Mikolajewska A, et al:. Epid Bull 2022; 44:3-9. doi: 10.25646/10753 
 
Healthcare use in 700 000 children and adolescents for six months after covid-19: before and after register based cohort study.
Magnusson K, Skyrud KD, Suren P, et al. BMJ. 2022 Jan 17;376:e066809. doi: 10.1136/bmj-2021-066809.
 
Long-Term Effects of COVID-19 on Workers in Health and Social Services in Germany.
Peters C, Dulon M, Westermann C, et al. Int J Environ Res Public Health. 2022 Jun 7;19(12):6983. doi: 10.3390/ijerph19126983.
 
Gesundheitsreport 2022 – Zwei Jahre Coronapandemie: Wie geht es Deutschlands Beschäftigten? Techniker Krankenkasse (TK). (2022). Teil 2. 2022 Jul. Verfügbar unter: https://www.tk.de 
 
Taking pandemic sequelae seriously: from the Russian influenza to COVID-19 long-haulers.
Honigsbaum M, Krishnan L. Lancet. 2020 Oct 31;396(10260):1389-1391. doi: 10.1016/S0140-6736(20)32134-6. 
 
Über 60 Prozent der Patient:innen mit Post-COVID-19-Diagnose nur in einem Quartal in vertragsärztlicher Behandlung.
Monitor Versorgungsforschung. 2022 Apr 24.
 
Krankschreibungen aufgrund von Long-COVID: Wenige Betroffene, aber lange krankheitsbedingte Ausfallzeiten
Willenborg, P. idw – Informationsdienst Wissenschaft. 2022 Sep 14. Verfügbar unter: idw-online.de

Koruma/risk faktörleri

Risk Factors Associated With Post-COVID-19 Condition: A Systematic Review and Meta-analysis.
Tsampasian V, Elghazaly H, Chattopadhyay R, et al. JAMA Intern Med. 2023 Jun 1;183(6):566-580. doi: 10.1001/jamainternmed.2023.0750.
 
Prevalence of long COVID decreases for increasing COVID-19 vaccine uptake.
De Domenico M. PLOS Glob Public Health. 2023 Jun 21;3(6):e0001917. doi: 10.1371/journal.pgph.0001917. 
 
Prevalence and risk factors of long COVID 6-12 months after infection with the Omicron variant among nonhospitalized patients in Hong Kong.
Luo J, Zhang J, Tang HT, et al. J Med Virol. 2023 Jun;95(6):e28862. doi: 10.1002/jmv.28862.
 
Acute and post-acute sequelae of SARS-CoV-2 infection: a review of risk factors and social determinants.
Wang C, Ramasamy A, Verduzco-Gutierrez M, Brode WM, Melamed E. Virol J. 2023 Jun 16;20(1):124. doi: 10.1186/s12985-023-02061-8.
 
Persistent symptoms and risk factors predicting prolonged time to symptom-free after SARS‑CoV‑2 infection: an analysis of the baseline examination of the German COVIDOM/NAPKON-POP cohort.
Shi Y, Strobl R, Apfelbacher C, et al. Infection. 2023 May 25:1-16. doi: 10.1007/s15010-023-02043-6. Online ahead of print.
 
Risk factors for post-COVID-19 condition (Long Covid) in children: a prospective cohort study.
Morello R, Mariani F, Mastrantoni L, et al. EClinicalMedicine. 2023 May;59:101961. doi: 10.1016/j.eclinm.2023.101961. 
 
Post-acute sequelae after SARS-CoV-2 infection by viral variant and vaccination status: a multicenter cross-sectional study.
Kahlert CR, Strahm C, Güsewell S, et al. Clin Infect Dis. 2023 Mar 11:ciad143. doi: 10.1093/cid/ciad143. Online ahead of print.
 
Effect of covid-19 vaccination on long covid: systematic review.
Byambasuren O, Stehlik P, Clark J, et al. BMJ Med. 2023 Feb 1;2(1):e000385. doi: 10.1136/bmjmed-2022-000385. 
 
Post COVID-19 condition after Wildtype, Delta, and Omicron SARS-CoV-2 infection and prior vaccination: Pooled analysis of two population-based cohorts.
Ballouz T, Menges D, Kaufmann M, et al. PLoS One. 2023 Feb 22;18(2):e0281429. doi: 10.1371/journal.pone.0281429. 
 
Factors Associated With Long COVID Symptoms in an Online Cohort Study.
Durstenfeld MS, Peluso MJ, Peyser ND, et al. Open Forum Infect Dis. 2023 Feb 1;10(2):ofad047. doi: 10.1093/ofid/ofad047. 
 
Post-covid medical complaints following infection with SARS-CoV-2 Omicron vs Delta variants.
Magnusson K, Kristoffersen DT, Dell'Isola A, et al. Nat Commun. 2022 Nov 30;13(1):7363. doi: 10.1038/s41467-022-35240-2.
 
Symptoms and risk factors for long COVID in non-hospitalized adults.
Subramanian A, Nirantharakumar K, Hughes S, et al. Nat Med. 2022 Aug;28(8):1706-1714. doi: 10.1038/s41591-022-01909-w. 
 
Impact of COVID-19 vaccination on the risk of developing long-COVID and on existing long-COVID symptoms: A systematic review.
Notarte KI, Catahay JA, Velasco JV, et al. EClinicalMedicine. 2022 Aug 27;53:101624. doi: 10.1016/j.eclinm.2022.101624.
 
Multiple early factors anticipate post-acute COVID-19 sequelae.
Su Y, Yuan D, Chen DG, et al. Cell. 2022 Mar 3;185(5):881-895.e20. doi: 10.1016/j.cell.2022.01.014. 
 
Age, Sex and Previous Comorbidities as Risk Factors Not Associated with SARS-CoV-2 Infection for Long COVID-19: A Systematic Review and Meta-Analysis.
Notarte KI, de Oliveira MHS, Peligro PJ, et al. J Clin Med. 2022 Dec 9;11(24):7314. doi: 10.3390/jcm11247314.
 
Long-lasting Symptoms After an Acute COVID-19 Infection and Factors Associated With Their Resolution.
Robineau O, Zins M, Touvier M, et al. JAMA Netw Open. 2022 Nov 1;5(11):e2240985. doi: 10.1001/jamanetworkopen.2022.40985.
 
Effect of COVID-19 Vaccines on Reducing the Risk of Long COVID in the Real World: A Systematic Review and Meta-Analysis.
Gao P, Liu J, Liu M. Int J Environ Res Public Health. 2022 Sep 29;19(19):12422. doi: 10.3390/ijerph191912422.
 
Prevalence and risk factors of post-COVID-19 condition in adults and children at 6 and 12 months after hospital discharge: a prospective, cohort study in Moscow (StopCOVID).
Pazukhina E, Andreeva M, Spiridonova E, et al. BMC Med. 2022 Jul 6;20(1):244. doi: 10.1186/s12916-022-02448-4.
 
Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records.
Thompson EJ, Williams DM, Walker AJ, et al. Nat Commun. 2022 Jun 28;13(1):3528. doi: 10.1038/s41467-022-30836-0.

Prevalans, insidans

How common is long COVID? Why studies give different answers.
Ledford H. Nature. 2022 Jun;606(7916):852-853. doi: 10.1038/d41586-022-01702-2.
 
One-Year Temporal Changes in Long COVID Prevalence and Characteristics: A Systematic Review and Meta-Analysis.
Huang Q, Jia M, Sun Y, et al. Value Health. 2023 Jun;26(6):934-942. doi: 10.1016/j.jval.2022.11.011. 

Prevalence of long COVID complaints in persons with and without COVID-19.
Magnusson K, Turkiewicz A, Flottorp SA, et al. Sci Rep. 2023 Apr 13;13(1):6074. doi: 10.1038/s41598-023-32636-y.
 
Post-COVID-19 condition in the German working population: A cross-sectional study of 200,000 registered stem cell donors.
Bernas SN, Baldauf H, Real R, et al. J Intern Med. 2023 Mar;293(3):354-370. doi: 10.1111/joim.13587. 
 
Pooled Prevalence of Long COVID-19 Symptoms at 12 Months and Above Follow-Up Period: A Systematic Review and Meta-Analysis.
Mudgal SK, Gaur R, Rulaniya S, et al. Cureus. 2023 Mar 18;15(3):e36325. doi: 10.7759/cureus.36325. 
 
Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK.
Office for National Statistics (ONS). 2023 Mar 30. Verfügbar unter: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/30march2023
 
The prevalence and long-term health effects of Long Covid among hospitalised and non-hospitalised populations: A systematic review and meta-analysis.
O'Mahoney LL, Routen A, Gillies C, et.al. EClinicalMedicine. 2022 Dec 1;55:101762. doi: 10.1016/j.eclinm.2022.101762. 
 
Prevalence and clinical presentation of long COVID in children: a systematic review.
Pellegrino R, Chiappini E, Licari A, et al. Eur J Pediatr. 2022 Dec;181(12):3995-4009. doi: 10.1007/s00431-022-04600-x. Epub 2022 Sep 15.
 
Global Prevalence of Post-Coronavirus Disease 2019 (COVID-19) Condition or Long COVID: A Meta-Analysis and Systematic Review.
Chen C, Haupert SR, Zimmermann L, et al. J Infect Dis. 2022 Nov 1;226(9):1593-1607. doi: 10.1093/infdis/jiac136.
 
A population-based serological study of post-COVID syndrome prevalence and risk factors in children and adolescents.
Dumont R, Richard V, Lorthe E, et al. 2022 Nov 29;13(1):7086. doi: 10.1038/s41467-022-34616-8.
 
Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symptom Clusters Following Symptomatic COVID-19 in 2020 and 2021.
Global Burden of Disease Long COVID Collaborators; Wulf Hanson S, Abbafati C, Aerts JG et al. JAMA. 2022 Oct 25;328(16):1604-1615. doi: 10.1001/jama.2022.18931.
 
Prevalence of post COVID-19 condition symptoms: a systematic review and meta-analysis of cohort study data, stratified by recruitment setting
European Centre for Disease Prevention and Control (ECDC). 2022 Oct 31. Verfügbar unter: https://www.ecdc.europa.eu/en/publications-data/prevalence-post-covid-19-condition-symptoms-systematic-review-and-meta-analysis
 
Post-COVID-19 conditions in children and adolescents diagnosed with COVID-19.
Kostev K, Smith L, Koyanagi A, et al. Pediatr Res. 2022 May 14:1-6. doi: 10.1038/s41390-022-02111-x. Online ahead of print. 

Epidemiyoloji ve halk sağlığı

Recovery and symptom trajectories up to two years after SARS-CoV-2 infection: population based, longitudinal cohort study.
Ballouz T, Menges D, Anagnostopoulos A, et al. BMJ. 2023 May 31;381:e074425. doi: 10.1136/bmj-2022-074425.

A Systematic Review of Persistent Clinical Features After SARS-CoV-2 in the Pediatric Population.
Jiang L, Li X, Nie J, et al. 2023 Jul 21:e2022060351. doi: 10.1542/peds.2022-060351. Online ahead of print.

Understanding How Post-COVID-19 Condition Affects Adults and Health Care Systems.
Katz GM, Bach K, Bobos P, et al. JAMA Health Forum. 2023 Jul 7;4(7):e231933. doi: 10.1001/jamahealthforum.2023.1933.

SARS-CoV-2 post-acute sequelae in previously hospitalised patients: systematic literature review and meta-analysis.
Kelly et al. Eur Respir Rev. 2023 Jul 12;32(169):220254. doi: 10.1183/16000617.0254-2022. Print 2023 Sep 30.

Post-COVID Conditions. 
Mueller MR, Ganesh R, Hurt RT, et al. Mayo Clin Proc. 2023 Jul;98(7):1071-1078. doi: 10.1016/j.mayocp.2023.04.007.

Post-acute sequelae of COVID-19: understanding and addressing the burden of multisystem manifestations.
Parotto M, Gyöngyösi M, Howe K, et al. Lancet Respir Med. 2023 Jul 17:S2213-2600(23)00239-4. doi: 10.1016/S2213-2600(23)00239-4. Online ahead of print.

New-onset neurodegenerative diseases as long-term sequelae of SARS-CoV-2 infection: A systematic review and meta-analysis.
Rahmati M, Yon DK, Lee SW, et al. J Med Virol. 2023 Jul;95(7):e28909. doi: 10.1002/jmv.28909.

Long COVID in Children: A Multidisciplinary Review.
Sansone F, Pellegrino GM, Caronni A, et al. Diagnostics (Basel). 2023 Jun 7;13(12):1990. doi: 10.3390/diagnostics13121990.

Neuropsychological deficits in patients with persistent COVID-19 symptoms: a systematic review and meta-analysis.
Sobrino-Relaño S, Balboa-Bandeira Y, Peña J, et al. Sci Rep. 2023 Jun 26;13(1):10309. doi: 10.1038/s41598-023-37420-6.

A scoping review of persistent symptoms after COVID infection at different follow-up periods.
Sreelakshmi PR, Tandale BV, Jadhav AV, et al. Indian J Public Health. 2023 Apr-Jun;67(2):292-300. doi: 10.4103/ijph.ijph_1178_22.

Postacute sequelae of COVID-19 at 2 years.
Bowe B, Xie Y, Al-Aly Z.Nat Med. 2023 Sep;29(9):2347-2357. doi: 10.1038/s41591-023-02521-2. Epub 2023 Aug 21. 

Incidence of long COVID-19 in people with previous SARS-Cov2 infection: a systematic review and meta-analysis of 120,970 patients.  
Di Gennaro F, Belati A, Tulone O, et al. Intern Emerg Med. 2023 Aug;18(5):1573-1581. doi: 10.1007/s11739-022-03164-w. Epub 2022 Nov 30. 

Long-term health consequences among individuals with SARS-CoV-2 infection compared to individuals without infection: results of the population-based cohort study CoMoLo Follow-up.
Heidemann C, Sarganas G, Du Y, et al. BMC Public Health. 2023 Aug 21;23(1):1587. doi: 10.1186/s12889-023-16524-8. 

Characterization of post-COVID syndromes by symptom cluster and time period up to 12 months post-infection: A systematic review and meta-analysis. 
Kuodi P, Gorelik Y, Gausi B, et al. Int J Infect Dis. 2023 Sep;134:1-7. doi: 10.1016/j.ijid.2023.05.003. Epub 2023 May 6. 

Long-term symptom severity and clinical biomarkers in post-COVID-19/chronic fatigue syndrome: results from a prospective observational cohort. 
Legler F, Meyer-Arndt L, Mödl L, et al. EClinicalMedicine. 2023 Aug 19;63:102146. doi: 10.1016/j.eclinm.2023.102146. eCollection 2023 Sep. 

Symptom Profiles of Children and Young People 12 Months after SARS-CoV-2 Testing: A National Matched Cohort Study (The CLoCk Study). 
Pinto Pereira SM, Nugawela MD, McOwat K, et al. Children (Basel). 2023 Jul 14;10(7):1227. doi: 10.3390/children10071227.

S1 guidelines for the management of postviral conditions using the example of post-COVID-19.
Rabady S, Hoffmann K, Aigner M, et al. Wien Klin Wochenschr. 2023 Jul;135(Suppl 4):525-598. doi: 10.1007/s00508-023-02242-z. Epub 2023 Aug 9. 

Epidemiology, clinical presentation, pathophysiology, and management of long COVID: an update. 
Su S, Zhao Y, Zeng N, et al. Mol Psychiatry. 2023 Jul 25. doi: 10.1038/s41380-023-02171-3. Online ahead of print.

15-month post-COVID syndrome in outpatients: Attributes, risk factors, outcomes, and vaccination status - longitudinal, observational, case-control study.    
Augustin M, Stecher M, Wüstenberg H, et al. Front Immunol. 2023 Sep 12;14:1226622. doi: 10.3389/fimmu.2023.1226622. eCollection 2023.    
    
True prevalence of long COVID in children: a narrative review.    
Esposito S, Deolmi M, Ramundo G, et al. 2023 Sep 14;14:1225952. doi: 10.3389/fmicb.2023.1225952. eCollection 2023.    
    
Impact of COVID-19 critical illness on functional status, fatigue symptoms, and health-related quality of life one-year after hospital discharge: a systematic review and meta-analysis.    
Gesser AF, Campos ML, Artismo RS, et al. 2023 Oct 11:1-12. doi: 10.1080/09638288.2023.2266365. Online ahead of print.    
    
Risk factors associated with post-acute sequelae of SARS-CoV-2: an N3C and NIH RECOVER study.    
Hill EL, Mehta HB, Sharma S, et al. BMC Public Health. 2023 Oct 25;23(1):2103. doi: 10.1186/s12889-023-16916-w.    
    
Post COVID sequelae among COVID-19 survivors: insights from the Indian National Clinical Registry for COVID-19.    
Kumar G, Bhalla A, Mukherjee A, et al. BMJ Glob Health. 2023 Oct;8(10):e012245. doi: 10.1136/bmjgh-2023-012245.    
    
Prevalence and risk factors for persistent symptoms after COVID-19: a systematic review and meta-analysis     
Luo D, Mei B, Wang P, et al. Clin Microbiol Infect. 2023 Oct 20:S1198-743X(23)00526-8. doi: 10.1016/j.cmi.2023.10.016. Online ahead of print.    
    
Prevalence and risk factors for long COVID and post-COVID-19 condition in Africa: a systematic review.    
Müller SA, Isaaka L, Mumm R, et al. Lancet Glob Health. 2023 Nov;11(11):e1713-e1724. doi: 10.1016/S2214-109X(23)00384-4.   

Long-term health impacts of COVID-19 among 242,712 adults in England.           
Atchison CJ, Davies B, Cooper E, et al. Nat Commun. 2023 Oct 24;14(1):6588. doi: 10.1038/s41467-023-41879-2.      

Core outcome measurement instruments for use in clinical and research settings for adults with post-COVID-19 condition: an international Delphi consensus study.    
Gorst SL, Seylanova N, Dodd SR, et al.; PC-COS study group.Lancet Respir Med. 2023 Dec;11(12):1101-1114. doi: 10.1016/S2213-2600(23)00370-3. Epub 2023 Nov 2.    

Determinants of the onset and prognosis of the post-COVID-19 condition: a 2-year prospective observational cohort study.   
Mateu L, Tebe C, Loste C, et al. Lancet Reg Health Eur. 2023 Sep 5;33:100724. doi: 10.1016/j.lanepe.2023.100724. eCollection 2023 Oct.  

What do we mean by long COVID? A scoping review of the cognitive sequelae of SARS-CoV-2 infection.  
Nicotra A, Masserini F, Calcaterra F, et al. Eur J Neurol. 2023 Dec;30(12):3968-3978. doi: 10.1111/ene.16027. Epub 2023 Aug 26.  

Clinical Characterization of the Persistent COVID-19 Symptoms: A Descriptive Observational Study in Primary Care.  
Rodríguez Onieva A, Vallejo Basurte C, Fernández Bersabé A, et al. J Prim Care Community Health. 2023 Jan-Dec;14:21501319231208283. doi: 10.1177/21501319231208283.  

Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome - State of the art: Report of the 2nd international meeting at the Charité Fatigue Center. 
Steiner S, Fehrer A, Hoheisel F, et al. Autoimmun Rev. 2023 Nov;22(11):103452. doi: 10.1016/j.autrev.2023.103452. Epub 2023 Sep 22.

Allergic diseases as risk factors for Long-COVID symptoms: Systematic review of prospective cohort studies. 
Wolff D, Drewitz KP, Ulrich A, et al. Clin Exp Allergy. 2023 Nov;53(11):1162-1176. doi: 10.1111/cea.14391. Epub 2023 Nov 8.

Incidence of long-term post-acute sequelae of SARS-CoV-2 infection related to pain and other symptoms: A systematic review and meta-analysis.    
Hoshijima H, Mihara T, Seki H, et al. PLoS One. 2023 Nov 29;18(11):e0250909. doi: 10.1371/journal.pone.0250909. eCollection 2023    

The effect of the urban exposome on COVID-19 health outcomes: A systematic review and meta-analysis. 
Houweling L, Maitland-Van der Zee AH, Holtjer JCS, et al. Environ Res. 2024 Jan 1;240(Pt 2):117351. doi: 10.1016/j.envres.2023.117351. Epub 2023 Oct 17   

Covid-19 vaccine effectiveness against post-covid-19 condition among 589 722 individuals in Sweden: population based cohort study.  
Lundberg-Morris L, Leach S, Xu Y, et al. BMJ. 2023 Nov 22;383:e076990. doi: 10.1136/bmj-2023-076990.

The effectiveness of COVID-19 vaccine in the prevention of post-COVID conditions: a systematic literature review and meta-analysis of the latest research.  
Marra AR, Kobayashi T, Callado GY, et al. Antimicrob Steward Healthc Epidemiol. 2023 Oct 13;3(1):e168. doi: 10.1017/ash.2023.447. eCollection 2023.  

Association Between Duration of SARS-CoV-2 Positivity and Long COVID.  
Pozzi C, Sarti R, Levi R, et al. Clin Infect Dis. 2023 Nov 30;77(11):1531-1533. doi: 10.1093/cid/ciad434. 

Risk factors for long COVID in children and adolescents: a systematic review and meta-analysis.  
Rayner DG, Wang E, Su C, et al. World J Pediatr. 2023 Oct 27. doi: 10.1007/s12519-023-00765-z. Online ahead of print.

The burden of persistent symptoms after COVID-19 (long COVID): a meta-analysis of controlled studies in children and adults.  
Azzam A, Khaled H, Refaey N, et al. Virol J. 2024 Jan 11;21(1):16. doi: 10.1186/s12985-024-02284-3.  

Post-COVID health policy responses to healthcare workforce capacities: A comparative analysis of health system resilience in six European countries.  
Burau V, Mejsner SB, Falkenbach M, et al. Health Policy. 2024 Jan;139:104962. doi: 10.1016/j.healthpol.2023.104962. Epub 2023 Dec 13.  

The effectiveness of COVID-19 vaccines to prevent long COVID symptoms: staggered cohort study of data from the UK, Spain, and Estonia.  
Català M, Mercadé-Besora N, Kolde R, et al. Lancet Respir Med. 2024 Jan 11:S2213-2600(23)00414-9. doi: 10.1016/S2213-2600(23)00414-9. Online ahead of print. 

Serological markers and long COVID – A rapid systematic review. 
Collins E, Philippe E, Gravel CA, et al. Eur J Clin Invest. 2023 Dec 11:e14149. doi: 10.1111/eci.14149. Online ahead of print. 

Epidemiology of 7375 children and adolescents hospitalized with COVID-19 in Germany, reported via a prospective, nationwide surveillance study in 2020-2022. 
Doenhardt M, Hufnagel M, Diffloth N, et al. Sci Rep. 2024 Jan 2;14(1):47. doi: 10.1038/s41598-023-49210-1. 

Cardiovascular autonomic dysfunction in post-COVID-19 syndrome: a major health-care burden. 
Fedorowski A, Fanciulli A, Raj SR, et al. Nat Rev Cardiol. 2024 Jan 2. doi: 10.1038/s41569-023-00962-3. Online ahead of print. 

Persistence of post-COVID symptoms in the general population two years after SARS-CoV-2 infection: A systematic review and meta-analysis. 
Fernandez-de-Las-Peñas C, Notarte KI, Macasaet R, et al. J Infect. 2024 Feb;88(2):77-88. doi: 10.1016/j.jinf.2023.12.004. Epub 2023 Dec 13. 

Long COVID or Post-COVID-19 Condition: Past, Present and Future Research Directions. 
Fernández-de-Las-Peñas C, Raveendran AV, Giordano R, et al. Microorganisms. 2023 Dec 11;11(12):2959. doi: 10.3390/microorganisms11122959. 

Is antiviral treatment at the acute phase of COVID-19 effective for decreasing the risk of long-COVID? A systematic review. 
Fernández-de-Las-Peñas C, Torres-Macho J, Catahay JA, et al.  Infection. 2024 Feb;52(1):43-58. doi: 10.1007/s15010-023-02154-0. Epub 2023 Dec 19. 

Applicability of heart rate variability for cardiac autonomic assessment in long-term COVID patients: A systematic review. 
Ferreira ÁA, Abreu RM, Teixeira RS, et al. J Electrocardiol. 2024 Jan-Feb;82:89-99. doi: 10.1016/j.jelectrocard.2023.12.002. Epub 2023 Dec 12. 

Incidence and burden of long COVID in Africa: a systematic review and meta-analysis. 
Frallonardo L, Segala FV, Chhaganlal KD, et al. Sci Rep. 2023 Dec 6;13(1):21482. doi: 10.1038/s41598-023-48258-3. 

Risk factors for long coronavirus disease 2019 (long COVID) among healthcare personnel, Brazil, 2020-2022. 
Marra AR, Sampaio VS, Ozahata MC, et al. Infect Control Hosp Epidemiol. 2023 Dec;44(12):1972-1978. doi: 10.1017/ice.2023.95. Epub 2023 Jun 5. 

Pediatric and adult patients with ME/CFS following COVID-19: A structured approach to diagnosis using the Munich Berlin Symptom Questionnaire (MBSQ). 
Peo LC, Wiehler K, Paulick J, et al. Eur J Pediatr. 2023 Dec 14. doi: 10.1007/s00431-023-05351-z. Online ahead of print. 

Correction: Prevalence of mental health problems among children with long COVID: A systematic review and meta-analysis. 
PLOS ONE Staff. PLoS One. 2023 Dec 14;18(12):e0296160. doi: 10.1371/journal.pone.0296160. eCollection 2023. 

Vaccine Effectiveness Against Long COVID in Children. 
Razzaghi H, Forrest CB, Hirabayashi K, et al. Pediatrics. 2024 Jan 16. Doi: 10.1542/peds.2023-064446. Online ahead of print. 

Long-Term Effects of COVID-19 on the Cardiopulmonary System in Adults and Children: Current Status and Questions to be Resolved by the National Institutes of Health Researching COVID to Enhance Recovery Initiative. 
Rischard F, Altman N, Szmuszkovicz J, et al. Chest. 2024 Jan 6:S0012-3692(24)00006-0. Doi: 10.1016/j.chest.2023.12.030. Online ahead of print. 

Return to work after Post-COVID: describing affected employees' perceptions of personal resources, organizational offerings and care pathways. 
Straßburger C, Hieber D, Karthan M, et al. Front Public Health. 2023 Nov 27;11:1282507. Doi: 10.3389/fpubh.2023.1282507. eCollection 2023. 

Looking at the Data on Smoking and Post-COVID-19 Syndrome – A Literature Review. 
Trofor AC, Robu Popa D, Melinte OE, et al. J Pers Med. 2024 Jan 16;14(1):97. Doi: 10.3390/jpm14010097. 

Definition and measurement of post-COVID-19 conditions in real-world practice: a global systematic literature review. 
Yang J, Markus K, Andersen KM, et al. BMJ Open. 2024 Jan 17;14(1):e077886. Doi: 10.1136/bmjopen-2023-077886. 

Long-term outcomes following hospital admission for COVID-19 versus seasonal influenza: a cohort study. 
Xie Y, Choi T, Al-Aly Z. Lancet Infect Dis. 2023 Dec 14:S1473-3099(23)00684-9. Doi: 10.1016/S1473-3099(23)00684-9. Online ahead of print. 

Preinfection Neutralizing Antibodies, Omicron BA.5 Breakthrough Infection, and Long COVID: A Propensity Score-Matched Analysis. 
Yamamoto S, Matsuda K, Maeda K, et al. J Infect Dis. 2023 Dec 20 ;228(12) :1652-1661. Doi : 10.1093/infdis/jiad317. 

Long COVID is associated with severe cognitive slowing: a multicentre cross-sectional study. 
Zhao S, Martin EM, Reuken PA, et al. EClinicalMedicine. 2024 Jan 25;68:102434. doi: 10.1016/j.eclinm.2024.102434. eCollection 2024 Feb. 

Prevalence and determinants of post-acute sequelae after SARS-CoV-2 infection (Long COVID) among adults in Mexico during 2022: a retrospective analysis of nationally representative data.  
Bello-Chavolla OY, Fermín-Martínez CA, Ramírez-García D, et al. Lancet Reg Health Am. 2024 Feb 3;30:100688. doi: 10.1016/j.lana.2024.100688. eCollection 2024 Feb.  

Cognitive domains affected post-COVID-19; a systematic review and meta-analysis.  
Fanshawe JB, Sargent BF, Badenoch JB, et al. Eur J Neurol. 2024 Feb 20:e16181. doi: 10.1111/ene.16181. Online ahead of print.  

Post-covid-19 conditions in adults: systematic review and meta-analysis of health outcomes in controlled studies. 
Franco JVA, Garegnani LI, Metzendorf MI, et al. BMJ Med. 2024 Jan 29;3(1):e000723. doi: 10.1136/bmjmed-2023-000723. eCollection 2024. 

Prevalence and trajectories of post-COVID-19 neurological manifestations: A systematic-review and meta-analysis. 
Giussani G, Westenberg E, Garcia-Azorin D, et al. Neuroepidemiology. 2024 Jan 25. doi: 10.1159/000536352. Online ahead of print. 

Core outcome measurement instruments for use in clinical and research settings for adults with post-COVID-19 condition: an international Delphi consensus study. 
Gorst SL, Seylanova N, Dodd SR, et al. Lancet Respir Med. 2023 Dec;11(12):1101-1114. doi: 10.1016/S2213-2600(23)00370-3. Epub 2023 Nov 2. 

Blood-brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment. 
Greene C, Connolly R, Brennan D, et al. Nat Neurosci. 2024 Feb 22. doi: 10.1038/s41593-024-01576-9. Online ahead of print. 

Vaccination and the risk of post-acute sequelae after COVID-19 in the Omicron-predominant period. 
Huh K, Kim YE, Bae GH, et al. Clin Microbiol Infect. 2024 Feb 6:S1198-743X(24)00054-5. doi: 10.1016/j.cmi.2024.01.028. Online ahead of print. 

Social Inequalities in Long-Term Health Effects After COVID-19 – A Scoping Review. 
Lammers N, Beese F, Hoebel J, et al. Int J Public Health. 2024 Feb 7; 69:1606739. doi: 10.3389/ijph.2024.1606739. eCollection 2024. 

Multimorbidity and frailty are associated with poorer SARS-CoV-2-related outcomes: systematic review of population-based studies. 
Makovski TT, Ghattas J, Monnier-Besnard S, et al. Aging Clin Exp Res. 2024 Feb 14;36(1):40. doi: 10.1007/s40520-023-02685-4. 

SARS-CoV-2 Infection and Risk of Postacute Psychiatric and Neurologic Diagnoses: A Nationwide Danish Cohort Study. 
Nielsen NM, Spiliopoulos L, Hansen JV, et al. Neurology. 2024 Mar 12;102(5):e208113. doi: 10.1212/WNL.0000000000208113. Epub 2024 Feb 21. 

Association of psychiatric disorders with clinical diagnosis of long COVID in US veterans. 
Nishimi K, Neylan TC, Bertenthal D, et al. Psychol Med. 2024 Feb 5:1-9. doi: 10.1017/S0033291724000114. Online ahead of print. 

Navigating the Spectrum of Two Pediatric COVID-19 Complications: Multi-System Inflammatory Syndrome in Children and Post-Acute Sequelae of SARS-CoV-2 Infection. 
Parzen-Johnson S, Katz BZ. J Clin Med. 2024 Feb 18;13(4):1147. doi: 10.3390/jcm13041147. 

Association of vaccine status, reinfections, and risk factors with Long COVID syndrome. 
Romero-Ibarguengoitia ME, Rodríguez-Torres JF, Garza-Silva A, et al. Sci Rep. 2024 Feb 2;14(1):2817. doi: 10.1038/s41598-024-52925-4. 

The global prevalence of depression, anxiety, and sleep disorder among patients coping with Post COVID-19 syndrome (long COVID): a systematic review and meta-analysis. 
Seighali N, Abdollahi A, Shafiee A, et al. BMC Psychiatry. 2024 Feb 6;24(1):105. doi: 10.1186/s12888-023-05481-6. 

Core Outcome Measurement Set for Research and Clinical Practice in Post COVID-19 Condition (Long COVID) in Children and Young People: An International Delphi Consensus Study "PC-COS Children". 
Seylanova N, Chernyavskaya A, Degtyareva N, et al. Eur Respir J. 2024 Feb 15:2301761. doi: 10.1183/13993003.01761-2023. Online ahead of print. 

Long COVID in pediatrics-epidemiology, diagnosis, and management. 
Toepfner N, Brinkmann F, Augustin S, et al. Eur J Pediatr. 2024 Jan 27. doi: 10.1007/s00431-023-05360-y. Online ahead of print. 

Cardiovascular disease as part of Long COVID: A systematic review. 
Tsampasian V, Bäck M, Bernardi M, et al. Eur J Prev Cardiol. 2024 Feb 21:zwae070. doi: 10.1093/eurjpc/zwae070. Online ahead of print. 

Associations between post-acute sequelae of SARS-CoV-2, COVID-19 vaccination and HIV infection: a United States cohort study. 
Yendewa GA, Perez JA, Patil N, McComsey GA. Front Immunol. 2024 Jan 22;15:1297195. doi: 10.3389/fimmu.2024.1297195. eCollection 2024.